Table of Contents

Abstract
Acknowledgements
Table of Contents
List of Tables
List of Figures
1. Literature Review
1.1 Breast Cancer
1.2 Estrogen Biology
1.3 Estrogen Receptor
1.4 Mechanism of Endocrine Resistance
1.5 Retinoids & Retinoic Acid Receptors
2.1 Prostate Cancer
2.2 Androgen Receptor
2.3 Mechanism of Development of Castrate Recurrent Prostate Cancer
2.4 The ETS Transcription Factors
2. Development of RARα Targeted Agents to Improve the Outcome of Hormonal Adjuvant Therapy in Breast Cancer
Abstract
Introduction
Materials and Methods
Results
Figures
Discussion
3. Disrupted Interaction of AR and Elk1 Leads to Decreased Cell Growth and
Proliferation of Prostate Cancer Cells
Abstract
Introduction
Materials and Methods
Results
Figures
Discussion
References